Isenzo esiyinhloko se-pharmacological sesithako esisebenzayo ku-Fluconix-340, i-nitroxinil, i-fasciolicidal.Isenzo esibulalayo ngokumelene ne-Fasciola hepatica siye saboniswa ku-vitro kanye ne-vivo ezilwaneni zaselabhorethri, nasezimvini nasezinkomeni.Indlela yokusebenza ingenxa yokuhlanganiswa kwe-phosphorylation ye-oxidative.Iphinde isebenze ngokumelene ne-triclabendazole-resistant
F. hepatica.
I-Fluconix-340 iboniswa ekwelapheni i-fascioliasis (infestations ye-Fasciola hepatica evuthiwe nengavuthiwe) ezinkomeni nasezimvini.Iyasebenza futhi, ngesilinganiso esinconyiwe somthamo, ngokumelene nokuhlasela kwabantu abadala kanye nezibungu ze-Haemonchus contortus ezinkomeni nasezimvini kanye ne-Haemonchus placei, i-Oesophagostomum radiatum kanye ne-Bunostomum phlebotomum ezinkomeni.
Ungasebenzisi ezilwaneni ezine-hypersensitivity eyaziwayo kusithako esisebenzayo.
Ungasebenzisi ezilwaneni ezikhiqiza ubisi oluzodliwa abantu.
Ungeqi umthamo oshiwo.
Ukuvuvukala okuncane kubonwa ngezikhathi ezithile endaweni yokujova ezinkomeni.Lokhu kungagwenywa ngokujova umthamo ezindaweni ezimbili ezihlukene kanye nokubhucunga kahle ukuze kuhlakazwe isisombululo.Ayikho imiphumela emibi yesistimu okufanele ilindelwe lapho izilwane (kuhlanganisa izinkomo ezikhulelwe nezinsikazi) zelashwa ngesilinganiso esivamile.
Ngomjovo ongaphansi kwesikhumba.Qinisekisa ukuthi umjovo awungeni umsipha ongaphansi kwesikhumba.Gqoka amagilavu angangenisi ukuze ugweme ukungcola nokucasuka kwesikhumba.Umthamo ojwayelekile ngu-10 mg nitroxinil ngekhilogremu yesisindo somzimba.
Izimvu: Nikeza ngokwesilinganiso semithamo elandelayo:
14 - 20 kg 0.5 ml 41 - 55 kg 1.5 ml
21 - 30 kg 0.75 ml 56 - 75 kg 2.0 ml
31 - 40 kg 1.0 ml > 75 kg 2.5 ml
Uma kuqubuka i-fascioliasis imvu ngayinye emhlambini kufanele ijovwe ngokushesha lapho ukubonakala kwalesi sifo kubonakala, kuphinda ukwelashwa njengoba kudingekile phakathi nesikhathi sokuhlaselwa kwe-infestation, ngezikhathi ezingekho ngaphansi kwenyanga eyodwa.
Izinkomo: 1.5 ml ye-Fluconix-340 nge-50 kg yesisindo somzimba.
Kokubili izilwane ezithelelekile kanye nezithintene nazo kufanele zelashwe, ukwelashwa kuphindwa njengoba kudingekile, nakuba kungavamile ukudlula kanye ngenyanga.Izinkomo zobisi kufanele zelashwe lapho zomile (okungenani izinsuku ezingama-28 ngaphambi kokuzala).
Qaphela: Ungasebenzisi ezilwaneni ezikhiqiza ubisi oluzodliwa abantu.
- Okwenyama:
Izinkomo: izinsuku ezingu-60.
Izimvu: izinsuku ezingama-49.
Gcina ngaphansi kuka-25ºC, endaweni epholile neyomile, futhi uvikele ekukhanyeni.