Albendazole Bolus 2500mg
I-Albendazole iyi-anthelmintic yokwenziwa eyingxenye ye-benzimidazole-derivatives esebenza ngokumelene nezikelemu eziningi kanye nezinga eliphezulu lomthamo futhi ngokumelene nezigaba zabantu abadala ze-fluke yesibindi.
Isenzo se-Pharmacological
I-Albendazole ihlanganiswe nephrotheni encane ye-eelworm futhi idlala indima.Ngemva kwe-albenzene ehlanganiswe ne-β-tubulin, ingavimbela ukufiphala phakathi kwe-albenzene ne-α tubulin ukuhlangana kuma-microtubules.Ama-Microtubules ayisakhiwo esiyisisekelo samayunithi amaseli amaningi.Ukuhlobana kwe-Albendazole ne-nematodes tubulin kuphakeme kakhulu kunokusondelana kwe-tubulin yezilwane ezincelisayo, ngakho-ke ubuthi ezilwaneni ezincelisayo buncane.
Izinkomba
I-Prophylaxis kanye nokwelashwa kwezikelemu ematholeni nasezinkomeni njenge:
Izikelemu ze-Gastrointestinal:I-Bunostomum, Cooperia, Chabertia, Haemonchus, Nematodirus, Oesophagostomum, Ostertagia, Strongyloides kanye ne-Trichostrongylus spp.
Izikelemu zamaphaphu:I-Dictyocaulus viviparus kanye ne-D. filaria.
Ama-tapeworms:Monieza spp.
I-Liver-fluke:omdala Fasciola hepatica.
I-Albendazole nayo inomphumela we-ovicidal.
Contra-izinkomba
Ukwelashwa ezinsukwini zokuqala ezingama-45 zokukhulelwa.
Okuqhamuka uma udla imishanguzo
Ukusabela kwe-Hypersensitivity.
Umthamo
Okokuphatha ngomlomo.
Okwezikelemu, ama-tapeworms:
Izinkomo / inyathi / ihhashi / izimvu / imbuzi: 5mg/kg isisindo somzimba
Inja / ikati: 10 kuya ku-25mg/kg isisindo somzimba
Okwe-flukes:
Izinkomo/izinyathi: 10mg/kg isisindo somzimba
Imvu/imbuzi: 7.5mg/kg isisindo somzimba
Amathole nezinkomo: 1 bolus nge-300 kg.isisindo somzimba.
Nge-fluke yesibindi:
1 bolus nge-250 kg.isisindo somzimba.
Isexwayiso
Gcina lapho izingane zingafinyeleleki khona.
Isikhathi Sokuqinisekisa
3 iminyaka.
Izikhathi Zokuhoxiswa
- Okwenyama:izinsuku ezingu-12.
- Ngobisi :4 izinsuku.
Isitoreji
Gcina endaweni epholile kakhulu, eyomile evikelekile ekukhanyeni.
Okokusetshenziswa Kwezilwane Kuphela, Gcina endaweni lapho izingane zingafinyeleleki khona
