Ingxenye eyinhloko yomjovo we-Dolamectin yi-dolamectin, ewuketshezi lwamafutha olungenambala noma oluphuzi.

1. I-Dolamectin umuthi obanzi wokulwa nezilokazane okhiqizwa ngokubiliswa kwe-Streptomyces aviticus ehlelwe kabusha ngokwezakhi zofuzo. Inomphumela omuhle wokuxosha kuma-endo-ectoparasites, ikakhulukazi amanye ama-nematode (izibungu eziyindilinga) nama-arthropod, kodwa ayinawo umphumela kuma-tapeworm, ama-fluke nama-protozoa. Indlela esebenza ngayo ikakhulukazi ukwandisa ukukhishwa kwe-inhibitory transmitter gamma-aminobutyric acid (GABA) esibunguni, ngaleyo ndlela ivimbele ukudluliselwa kwezimpawu zemizwa, ukuze amangqamuzana emisipha alahlekelwe amandla okufinyela, okuholela ekufeni kwesibungu. I-neurotransmitter ye-peripheral yezilwane ezincelisayo yi-acetylcholine futhi ayithinteki yi-dolamectin. I-Dolamectin akulula ukungena emgodleni wegazi nobuchopho, inomonakalo omncane ohlelweni lwezinzwa oluphakathi, futhi iphephile kakhulu ezifuyweni.

Kungumuthi we-macrolide olwa nezimbungulu osetshenziselwa ukwelapha izifo ezibangelwa yizimbungulu ezifana ne-nematodiasis, izintwala zegazi kanye ne-acariasis emfuyweni.

2. Izinyathelo Zokuqapha Ngomjovo we-doramectin Ukuphepha Kokusetshenziswa
Gcina kude nezingane. Abasebenzi akufanele badle noma babheme uma besebenzisa lo mkhiqizo, futhi kufanele bageze izandla ngemva kokuhlinzwa.
Kuxhomeke endaweni ezungezile
Okunobuthi ezinhlanzini nasezintweni eziphilayo zasemanzini, ukupakishwa kanye nezitsha zemithi esele akufanele kungcolise imithombo yamanzi.
Isici sokulondolozwa
Kunconywa ukuthi kugcinwe endaweni evaliwe endaweni emnyama. Umkhiqizo ubola ngokushesha futhi ungasebenzi ngaphansi kwelanga, futhi kufanele ugcinwe kude nokukhanya.

3. Ukusebenzisana kwezidakamizwa komjovo we-doramectin
Uma isetshenziswa kanye ne-ethylamine, kungase kube nokuphazamiseka okukhulu noma okubulalayo kwe-encephalopathy.