I-Enrofloxacin umuthi obulala amagciwane one-spectrum ebanzi wezilwane eziku-flurofenolone class. I-Escherichia coli, i-Salmonella, i-Klebsiella, i-Brucella, i-Pasteurella, i-Actinobacillus pleuropneumoniae, i-Erysipelas, i-Proteus, i-Serratia marcescens, i-Corynebacterium pyogenes, i-Portella septicarum Inomphumela omuhle kumabhaktheriya, i-Staphylococcus aureus, i-mycoplasma, i-chlamydia, njll., kodwa inomphumela obuthakathaka ku-Pseudomonas aeruginosa kanye ne-Streptococcus kanye nomphumela obuthakathaka kumabhaktheriya angenawo umoya. Inomphumela osobala wokulwa namagciwane kumabhaktheriya azwelayo.

Lo mkhiqizo umuncwa ngokushesha nangokuphelele ngomjovo we-intramuscular. Ukutholakala kwe-bioavailability yalo mkhiqizo kungu-91.9% ezingulubeni kanye no-82% ezinkomeni zobisi. Usatshalaliswa kabanzi ezilwaneni futhi ungangena kalula ezicutshini nasezintweni zomzimba. Ngaphandle koketshezi lwe-cerebrospinal, ukuhlushwa kwesidakamizwa cishe ezicutshini kuphakeme kunalokho okusegazini. Ukuguqulwa kwe-pulp. Isibindi kuhilela kakhulu ukususwa kweqembu le-ethyl lendandatho engu-7-crosin ukuze kukhiqizwe i-ciprofloxacin, kulandelwe yi-oxidation kanye ne-glucuronic acid conjugation, ekhishwa kakhulu ngezinso (ngokukhishwa kwe-renal tubular kanye nokuhlunga kwe-glomerular), 15% kuya ku-50% Kukhishwa kungashintshiwe emchameni. Khipha ingxenye Isikhathi sokuphila siyahlukahluka kakhulu ezinhlotsheni ezahlukene zezilwane kanye nezindlela ezahlukene zokuphathwa. Ukususwa kwengxenye yokuphila ngemva kokufakwa kwe-intramuscular.

ukusebenzisana kwemithi: (1) Lo mkhiqizo unomphumela wokubambisana uma uhlanganiswa noshukela wama-amino noma i-penicillin ene-spectrum ebanzi. (2) Ama-ion ensimbi esindayo njenge-Ca2+, i-Mg2+, i-Fe; kanye ne-Al Children angasebenzisana nalo mkhiqizo futhi athinte ukumuncwa. (3) Uma esetshenziswa kanye ne-theophylline kanye ne-caffeine, izinga lokubopha amaprotheni e-plasma lingancishiswa, ukuhlushwa kwe-theophylline kanye ne-caffeine egazini kuzokwanda ngendlela engavamile, futhi ngisho nezimpawu zobuthi be-theophylline zingase zivele. (4) Lo mkhiqizo unomphumela wokuvimbela ama-enzyme emithi yesibindi futhi unganciphisa izinga lokususwa kwemithi egaywa kakhulu esibindini.

Umsebenzi kanye nokusetshenziswa: Ama-antibiotic e-Flufenolone. Asetshenziselwa izifo zamagciwane kanye nokutheleleka kwe-mycoplasma emfuyweni nasezinkukhu.