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I-Niclosamide Bolus 1250 mg

Incazelo emfushane:

I-Niclosamide Bolus iyi-anthelmintic equkethe i-Niclosamide BP Vet, iyasebenza ngokumelene nezikelemu ze-tapeworm kanye nama-flue amathumbu afana ne-paramphistomum ezisuthi.


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

I-Niclosamide Bolus ivimbela i-phosphorylation ku-mitochondria ye-cestodes.Kokubili i-in vitro ne-vivo, i-scolex ne-proximal segment ibulawa lapho kuthintana nomuthi.I-scolex ekhululiwe ingase igaywe emathunjini;ngakho-ke, kungase kungenzeki ukuhlonza i-scolex endle.I-Niclosamide Bolus i-taenic acid esenzweni futhi ayigcini nje kuphela amasegimenti kodwa futhi i-scolex.

Umsebenzi we-Niclosamide Bolus ngokumelene nezikelemu ubonakala ubangelwa ukuvinjelwa kwe-mitochondrial oxidative phosphorylation;Ukukhiqizwa kwe-ATP ye-anaerobic nakho kuyathinteka.

Umsebenzi we-cestocidal we-Niclosamide Bolus ubangelwa ukuvinjwa kokumuncwa kwe-glucose yi-tapeworm kanye nokuqaqa inqubo ye-oxidative phosphorylation ku-mitochondria ye-cestodes.I-lactic acid eqoqiwe ebangelwa ukuvinjwa komjikelezo we-Krebs ibulala izikelemu.

Izinkomba

I-Niclosamide Bolus ikhonjiswe kuzo zombili izikelemu zetapeworm ezihlasela imfuyo, izinkukhu, izinja namakati kanye nakuma-immature paramphistomiasis (Amphistomiasis) yezinkomo, Izimvu nezimbuzi.

Izikelemu ze-tapeworm

Izinkomo, Izimbuzi Zezimvu kanye Nezinyamazane: I-Moniezia Species Thysanosoma (izikelemu ze-Fringed Tape)

Izinja: I-Dipylidium Caninum, i-Taenia Pisiformis T. hydatigena ne-T. taeniaeformis.

Amahhashi: Ukutheleleka kwe-Anoplocephalid

Izinkukhu: URaillietina noDavainea

I-Amphistomiasis: (I-Paramphistomes Engakabikho)

Ezinkomeni nasezimvini, i-Rumen flukes (izinhlobo ze-Paramphistomum) ivame kakhulu.Nakuba ama-flukes amadala axhunywe odongeni lwe-rumen angase abe nokubaluleka okuncane, lawo angavuthiwe adala umonakalo omkhulu nokufa ngenkathi efuduka odongeni lwe-duodenal.

Izilwane ezibonisa izimpawu ze-anorexia enzima, ukwanda kwamanzi, kanye nesifo sohudo esinamanzi kufanele kusolwelwe ukuthi sine-amphistomiasis futhi zelashwe ngokushesha nge-Niclosamide Bolus ukuvimbela ukufa nokulahlekelwa ukukhiqizwa njengoba i-Niclosamide Bolus ihlinzeka ngokusebenza ngempumelelo okuphezulu ngokungaguquguquki ezifweni ezingavuthiwe.

Ukwakheka

I-bolus ngayinye engagcotshiwe iqukethe:

I-Niclosamide IP 1.0 gm

Ukuphatha kanye nesilinganiso

I-Niclosamide Bolus ekuphakeleni noma kanjalo.

Ngokumelene nezikelemu zeTapeworms

Izinkomo, Izimvu Namahhashi: 1 gm bolus ngesisindo somzimba esingama-20 kg

Izinja namakati: 1 gm bolus ngesisindo somzimba esingu-10 kg

Izinkukhu: 1 gm bolus yezinyoni ezi-5 ezindala

(Cishe i-175 mg ngekhilogremu yesisindo somzimba)

Ngokumelene nama-Amphistomes

Izinkomo Nezimvu:Umthamo omkhulu ngesilinganiso se-1.0 gm bolus / 10 kg isisindo somzimba.

Ukuphepha:I-Niclosamide bolus inomkhawulo obanzi wokuphepha.Ukweqisa kwe-Niclosamide izikhathi ezingama-40 ezimvini nasezinkomeni kutholakale ukuthi akunabo ubuthi.Ezinjeni nasemakati, umthamo ophindwe kabili onconywayo awubangeli imiphumela emibi ngaphandle kokuthamba kwendle.I-Niclosamide bolus ingasetshenziswa ngokuphepha kuzo zonke izigaba zokukhulelwa nasezifundweni ezikhubazekile ngaphandle kwemiphumela emibi.


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